We aimed to determine the predictors of intensive care unit (ICU) admission or death in patients with Coronavirus Disease 2019 (COVID-19) pneumonia. This retrospective and single-center study includes patients aged ≥18 years who were diagnosed with COVID-19 pneumonia (laboratory and radiologically confirmed) between March 9 and April 8, 2020. Our composite endpoint was ICU admission or in-hospital death. To evaluate the factors in the composite endpoint, univariate and multivariate logistic regression analyses were performed. A total of 336 patients with COVID-19 pneumonia were recorded. The median age was 54 years [interquartile range (IQR): 21] and 187 (55.7%) were male. Fifty-one (15.2%) patients were admitted to the ICU. In-hospital death occurred in 33 (9.8%) patients. In univariate analysis, 17 parameters were associated with the composite endpoint and procalcitonin had the highest ODDs ratio (OR=36.568 CI=5.145-259.915). Our results revealed that body temperature (OR=1.489 CI=1.023-2.167, p=0.037), peripheral capillary oxygen saturation (SpO2) (OR=0.835 CI=0.773-0.901, p<0.001), and consolidation (>25%) in chest computed tomography (OR=3.170 CI=1.218-8.252, p=0.018) at admission were independent predictors. As a result, increased body temperature, decreased SpO2, a high level of procalcitonin, and degree of consolidation in chest computed tomography may predict a poor prognosis and have utility in the management of patients.

我们旨在确定 2019 年冠状病毒病 (COVID-19) 肺炎患者入住重症监护病房 (ICU) 或死亡的预测因素。这项回顾性单中心研究纳入了 2020 年 3 月 9 日至 4 月 8 日期间被诊断为 COVID-19 肺炎（实验室和放射学确诊）的≥18 岁患者。我们的复合终点是入住 ICU 或院内死亡。为了评估复合终点中的因素，进行了单变量和多变量逻辑回归分析。共记录了 336 名 COVID-19 肺炎患者。中位年龄为 54 岁 [四分位距 (IQR)：21]，其中 187 人 (55.7%) 为男性。51 名 (15.2%) 患者入住 ICU。33 名 (9.8%) 患者发生院内死亡。在单变量分析中，17 个参数与复合终点相关，降钙素原的 ODD 比最高（OR=36.568 CI=5.145-259.915）。我们的结果显示体温 (OR=1.489 CI=1.023-2.167, p=0.037)、外周毛细血管氧饱和度 (SpO2) (OR=0.835 CI=0.773-0.901, p<0.001) 和实变 (>25%)入院时胸部计算机断层扫描 (OR=3.170 CI=1.218-8.252, p=0.018) 是独立预测因子。因此，体温升高、SpO2 降低、降钙素原水平升高以及胸部 CT 中的实变程度可能预示着预后不良，并有助于患者的管理。入院时的外周毛细血管氧饱和度 (SpO2)（OR=0.835 CI=0.773-0.901，p<0.001）和实变（>25%）胸部 CT（OR=3.170 CI=1.218-8.252，p=0.018）是独立预测因子。因此，体温升高、SpO2 降低、降钙素原水平升高以及胸部 CT 中的实变程度可能预示着预后不良，并有助于患者的管理。入院时的外周毛细血管氧饱和度 (SpO2)（OR=0.835 CI=0.773-0.901，p<0.001）和胸部 CT 实变（>25%）（OR=3.170 CI=1.218-8.252，p=0.018）独立预测因子。因此，体温升高、SpO2 降低、降钙素原水平升高以及胸部 CT 中的实变程度可能预示着预后不良，并有助于患者的管理。