The root of Angelica sinensis (Oliv.) Diels, a well-known Chinese herbal medicine, has been used historically as hematopoietic and anti-inflammatory agents for thousands of years. Recent phytochemistry and pharmacological studies have proved that polysaccharides are one of the major active ingredients in A. sinensis. It has been demonstrated that ASPs (A. sinensis polysaccharides) had various important biological activities, such as hematopoietic, hepatoprotective, hypoglycemic, anti-inflammatory, antitumor, and antioxidant activities. The purpose of this present review is to appraise previous and current literatures on the extraction, purification, structural characterization and biological activities of ASPs. In addition, the structure–activity relationship will be further explored and discussed. We believe that this review will provide a useful bibliography for the investigation, production, and application of ASPs in functional foods and therapeutic agents. Moreover, this review also highlights the challenges of investigation and future considerations for holistic utilization.

中文翻译：

---

当归狄尔斯多糖的研究进展：提取，纯化，结构和生物活性

当归（著名的中草药）的根源在历史上已经用作造血和抗炎药已有数千年的历史了。最近的植物化学和药理研究已证明多糖是中华曲霉的主要活性成分之一。已经证明ASP（中华曲霉多糖）具有各种重要的生物学活性，例如造血，保肝，降血糖，抗炎，抗肿瘤和抗氧化活性。本综述的目的是评估有关ASP的提取，纯化，结构表征和生物学活性的现有文献和当前文献。此外，结构与活性之间的关系将得到进一步的探索和讨论。我们认为，本综述将为功能性食品和治疗剂中ASP的研究，生产和应用提供有用的参考书目。此外，本次审查还强调了调查的挑战以及整体利用的未来考虑因素。