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Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis
Chronic Respiratory Disease ( IF 3.5 ) Pub Date : 2021-03-17 , DOI: 10.1177/14799731211002240
Kevin Cares-Marambio 1 , Yessenia Montenegro-Jiménez 1 , Rodrigo Torres-Castro 1, 2 , Roberto Vera-Uribe 1, 2 , Yolanda Torralba 3, 4 , Xavier Alsina-Restoy 3 , Luis Vasconcello-Castillo 1, 2 , Jordi Vilaró 2, 5
Affiliation  

Knowledge on the sequelae of Coronavirus Disease 2019 (COVID-19) remains limited due to the relatively recent onset of this pathology. However, the literature on other types of coronavirus infections prior to COVID-19 reports that patients may experience persistent symptoms after discharge. To determine the prevalence of respiratory symptoms in survivors of hospital admission after COVID-19 infection. A living systematic review of five databases was performed in order to identify studies which reported the persistence of respiratory symptoms in COVID-19 patients after discharge. Two independent researchers reviewed and analysed the available literature, and then extracted and assessed the quality of those articles. Of the 1,154 reports returned by the initial search nine articles were found, in which 1,816 patients were included in the data synthesis. In the pooled analysis, we found a prevalence of 0.52 (CI 0.38–0.66, p < 0.01, I 2 = 97%), 0.37 (CI 0.28–0.48, p < 0.01, I 2 = 93%), 0.16 (CI 0.10–0.23, p < 0.01, I 2 = 90%) and 0.14 (CI 0.06–0.24, p < 0.01, I 2 = 96%) for fatigue, dyspnoea, chest pain, and cough, respectively. Fatigue, dyspnoea, chest pain, and cough were the most prevalent respiratory symptoms found in 52%, 37%, 16% and 14% of patients between 3 weeks and 3 months, after discharge in survivors of hospital admission by COVID-19, respectively.



中文翻译:

2019 年冠状病毒病 (COVID-19) 住院幸存者潜在呼吸道症状的患病率:系统评价和荟萃分析

由于 2019 年冠状病毒病 (COVID-19) 的发病时间相对较新,因此对它的后遗症的了解仍然有限。然而,有关 COVID-19 之前其他类型冠状病毒感染的文献报道称,患者出院后可能会出现持续症状。确定 COVID-19 感染后入院幸存者中呼吸道症状的患病率。对五个数据库进行了实时系统回顾,以确定报告 COVID-19 患者出院后呼吸道症状持续存在的研究。两名独立研究人员审查并分析了现有文献,然后提取并评估了这些文章的质量。在最初搜索返回的 1,154 份报告中,找到了 9 篇文章,其中 1,816 名患者纳入了数据综合。在汇总分析中,我们发现患病率为 0.52(CI 0.38–0.66,p < 0.01,I 2 = 97%)、0.37(CI 0.28–0.48,p < 0.01,I 2 = 93%)、0.16(CI 0.10)对于疲劳、呼吸困难、胸痛和咳嗽,分别为–0.23,p < 0.01 ,I 2 = 90%)和 0.14(CI 0.06-0.24,p < 0.01,I 2 = 96 % ) 。 疲劳、呼吸困难、胸痛和咳嗽是 COVID-19 住院幸存者出院后 3 周至 3 个月内最常见的呼吸道症状,分别为 52%、37%、16% 和 14% 。

更新日期:2021-03-17
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