Abstract

17α-methyltestosterone (MT) is an exogenous anabolic steroid hormone used widely in aquafarming. This study aimed to emphasize the environmental hazards of MT originated from a continuously operating masculinization pond with an intensive water recirculation system in Samut Prakan, Thailand. Risk quotient (RQ) and concentration factor (CF) were used to examine the ecological risk of MT in the pond environment. The results revealed relatively high MT concentrations in the water and sediments. These findings concurred the benefit of masculinization ponds with a water recirculation system in the way that it can effectively save the water and reduce the MT dosage that needs to be added into the feed. However, this could bring serious environmental concerns since releasing water containing MT residues and androgenic active metabolites through water overflowing from the masculinization pond to the environment during the wet season is inevitable. This is the first report indicating that CF relates to the androgenic potential activity and can be used to explain the ecological risk of MT contaminated water discharged from a full water recirculating earthen masculinization pond. This study provides important information indicating that CF values in a range of 7 to 16 are high enough to cause adversely affect the reproductive performance of tested fish (i.e., Probarbus jullieni, Barbonymus gonionotus, and Anabas testudineus).

摘要

17α-甲基睾酮 (MT) 是一种外源性合成代谢类固醇激素，广泛用于水产养殖。本研究旨在强调源自泰国北榄府一个具有集约化水再循环系统的连续运行的男性化池塘的 MT 的环境危害。风险商数（RQ）和浓度因子（CF）用于检测池塘环境中MT的生态风险。结果表明，水和沉积物中的 MT 浓度相对较高。这些发现同意带有水再循环系统的男性化池塘的好处，它可以有效地节约用水并减少需要添加到饲料中的 MT 剂量。然而，这可能会带来严重的环境问题，因为在雨季通过从男性化池塘溢出到环境中的水释放含有 MT 残留物和雄激素活性代谢物的水是不可避免的。这是第一份报告表明 CF 与雄激素潜在活动有关，可用于解释从全水再循环土制男性化池塘排放的 MT 污染水的生态风险。该研究提供了重要信息，表明 7 到 16 范围内的 CF 值足够高，足以对受试鱼的繁殖性能产生不利影响（即，这是第一份报告表明 CF 与雄激素潜在活动有关，可用于解释从全水再循环土制男性化池塘排放的 MT 污染水的生态风险。该研究提供了重要信息，表明 7 到 16 范围内的 CF 值足够高，足以对受试鱼的繁殖性能产生不利影响（即，这是第一份报告表明 CF 与雄激素潜在活动有关，可用于解释从全水再循环土制男性化池塘排放的 MT 污染水的生态风险。这项研究提供了重要信息，表明 7 到 16 范围内的 CF 值足够高，足以对受试鱼的繁殖性能产生不利影响（即，Probarbus jullieni、Barbonymus goninotus和Anabas testudineus )。