In this work, defective Zr-based metal–organic framework was successfully synthesized and evaluated as a dispersive micro-solid-phase extraction sorbent for efficient preconcentration and determination of fungicides in complex water samples. The defective Zr-based metal–organic framework crystal with increased adsorption capacity was successfully synthesized by employing formic acid as the modulator. The extraction conditions, including the pH, extraction time, desorption solvent and desorption time, were comprehensively investigated. Under optimum conditions, it was found that dispersive micro-solid-phase extraction method, coupled with liquid chromatography/mass spectrometry, exhibited a good linear relationship with correlation coefficients greater than 0.9980. The relative standard deviations of inter-day and intra-day precisions ranged from 2.6 to 9.2% and the limits of detection ranged from 0.004 to 0.036 μg/L. These merits, combined with their satisfactory recoveries (>80%), suggested the great potential of defective Zr-based metal–organic framework as a new adsorbent for efficient extraction of trace fungicides. This method exhibits good application potential for the pretreatment of fungicides from environmental water samples.

中文翻译：

---

缺陷的基于Zr的金属-有机骨架作为吸附剂，用于快速分散微固相萃取-液相色谱/质谱法测定环境水样中的杀真菌剂

在这项工作中，成功地合成了有缺陷的基于Zr的金属-有机骨架，并将其作为分散微固相萃取吸附剂进行了评估，以高效地对复杂水样品中的杀菌剂进行预浓缩和测定。以甲酸为调节剂，成功地合成了具有缺陷吸附能力的Zr基金属有机骨架晶体。考察了pH，萃取时间，脱附溶剂和脱附时间等萃取条件。在最佳条件下，发现分散微固相萃取法与液相色谱/质谱联用具有良好的线性关系，相关系数大于0.9980。日间和日内精度的相对标准偏差范围为2。检出限为6％至9.2％，范围为0.004至0.036μg/ L。这些优点，加上令人满意的回收率（> 80％），表明基于缺陷的Zr基金属-有机骨架作为高效吸附微量杀菌剂的新型吸附剂的巨大潜力。该方法具有良好的应用前景，可用于环境水样品中杀菌剂的预处理。