Reversal of atherosclerosis has been well documented in humans on intensive lifestyle changes or lipid-lowering therapies. The development of mouse models has greatly advanced our understanding of molecular mechanisms underlying this biological process. I seek to summarize the established mouse models and highlight the recent therapeutic progress on plaque regression.

中文翻译：

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动脉粥样硬化斑块消退：实验方法和治疗进展

动脉粥样硬化的逆转已在人类中充分证明，通过强化生活方式改变或降脂疗法。小鼠模型的发展极大地促进了我们对这一生物过程背后的分子机制的理解。我试图总结已建立的小鼠模型，并强调最近在斑块消退方面的治疗进展。