Abstract

The outbreak of SARS-CoV-2 resulted in more than 11 000 000 infections and over 530 000 deaths. Coronavirus (S) spike glycoproteins promote entry into cells and are the main target of antibodies. We studied the effect of electron beams on the SARS CoV-2 glycoprotein and also on RNA using Monte Carlo simulation. We demonstrated that S-SARS CoV peak glycoproteins damaged by irradiation electrons corresponding to an energy loss of approximately 1.2 keV with a damage rate of the efficiency that can be as high as \(68\%\).

中文翻译：

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聚焦SARS-CoV-2结构电子束辐照的蒙特卡罗模拟方法

摘要

SARS-CoV-2的爆发导致超过11000万例感染，超过53万例死亡。冠状病毒（S）刺突糖蛋白促进进入细胞，是抗体的主要靶标。我们使用蒙特卡洛模拟研究了电子束对SARS CoV-2糖蛋白以及RNA的影响。我们证明了S-SARS CoV峰值糖蛋白被辐照电子破坏，相当于能量损失约1.2 keV，效率的破坏率可高达\（68 \％\）。