Journal of Mathematical Biology ( IF 2.2 ) Pub Date : 2021-03-15 , DOI: 10.1007/s00285-021-01590-6 Frank P. Pijpers
In the spreading of infectious diseases, an important number to determine is how many other people will be infected on average by anyone who has become infected themselves. This is known as the reproduction number. This paper describes a non-parametric inverse method for extracting the full transfer function of infection, of which the reproduction number is the integral. The method is demonstrated by applying it to the timeline of hospitalisation admissions for covid-19 in the Netherlands up to May 20 2020, which is publicly available from the site of the Dutch National Institute of Public Health and the Environment (rivm.nl).
中文翻译:
确定流行病学繁殖数量的非参数方法
在传染病的传播中,要确定的一个重要数字是,被自己感染的人平均还会感染多少其他人。这被称为再现编号。本文描述了一种用于提取感染的全部传递函数的非参数逆方法,其中繁殖数是整数。该方法已通过将其应用到2020年5月20日在荷兰covid-19的住院治疗时间表中得到证明,该时间表可从荷兰国家公共卫生与环境研究所(rivm.nl)的网站上公开获得。