This opinion piece puts forward a critique of the policy and regulatory frameworks governing vaccines, understood as tools to confront pandemic and epidemic diseases (PEDs). Vaccines being the universally recognised prime method of prevention, immunisation campaigns and vaccine research and development (R&D) could reasonably be expected to feature prominently in any policy and/or strategic document addressing emerging health threats. Yet, vaccination occupies a relatively subsidiary role, with a prevalent focus on risk management mechanisms. This piece outlines the main characteristics of preparedness frameworks and looks at vaccine development in the course of PED outbreaks in the recent past, concluding that the COVID-19 pandemic calls for a paradigm shift in vaccine R&D, which should become integral to public health preparedness.

中文翻译：

---

重新思考疫苗开发作为欧洲卫生联盟准备工作的一个组成部分

这篇评论文章对管理疫苗的政策和监管框架提出了批评，这些框架被理解为应对大流行病和流行病 (PED) 的工具。疫苗是公认的预防、免疫运动和疫苗研发 (R&D) 的主要方法，可以合理地预期在任何应对新出现的健康威胁的政策和/或战略文件中占据显着位置。然而，疫苗接种占据了相对次要的角色，普遍关注风险管理机制。本文概述了防范框架的主要特征，并着眼于近期 PED 爆发过程中的疫苗开发，得出的结论是 COVID-19 大流行需要疫苗研发的范式转变，这应该成为公共卫生防范的组成部分。