Context

Spinal-generated movement disorders are a complex group of medical conditions, frequently misdiagnosed, originating in the spinal cord or from combined peripheral and central nervous system involvement. In this case report, we describe a novel form of position-dependent dyskinesia due to severe craniocervical malformation.

Findings

An 83-year-old woman with basilar invagination at the C2 vertebra above the line of Chamberlain, occipitocervical lordosis, platybasia with a short clivus, ankylosis of the C1–C2 complex and fusion of the C1 arch developed an unusual pattern of position-dependent left arm dyskinesia triggered by bending her neck forward with simultaneous contact of the flexed elbow with a flat surface. Symptoms did not improve with anticonvulsants and she progressed and died suddenly.

Conclusion/Clinical relevance

A newly described form of position-dependent arm dyskinesia can be associated with severe craniocervical malformation.

中文翻译：

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严重颅颈畸形引起的位置依赖性手臂运动障碍

语境

脊髓引起的运动障碍是一组复杂的医学病症，经常被误诊，起源于脊髓或外周和中枢神经系统受累。在本病例报告中，我们描述了一种由严重颅颈畸形引起的新型位置依赖性运动障碍。

发现

一名 83 岁的女性，张伯伦线以上的 C2 椎体基底内陷，枕颈前凸，斜坡短的扁平足，C1-C2 复合体强直和 C1 弓融合形成了一种不寻常的位置依赖性模式左臂运动障碍是由她的脖子向前弯曲同时弯曲的肘部接触平坦表面引发的。服用抗惊厥药后症状没有改善，她病情恶化并突然死亡。

结论/临床相关性

一种新描述的位置依赖性手臂运动障碍可能与严重的颅颈畸形有关。