ABSTRACT

The COVID-19 pandemic presents unique stressors (e.g. social isolation) that may increase substance use risk among young adults with a history of emotional disturbance. This study examined whether emotional disorder symptoms and transdiagnostic vulnerabilities during adolescence predicted young adult substance use during COVID-19, and whether using substances to cope with the pandemic’s social conditions mediated these associations. Adolescents (N = 2,120) completed baseline surveys assessing transdiagnostic emotional vulnerabilities (anhedonia, distress intolerance, anxiety sensitivity, negative urgency) and symptoms (major depression[MD], generalized anxiety[GAD], panic disorder[PD], social phobia[SP], obsessive-compulsive disorder[OCD]) in adolescence (September–December 2016; M[SD] age = 17.45[0.38]). At follow-up (May–August 2020; M[SD] age = 21.16[0.39]), past 30-day substance use and using substances to cope with social isolation during the pandemic were reported. Adjusted models showed that baseline distress intolerance, anxiety sensitivity, negative urgency, and MD symptoms each significantly predicted higher number of past-month single-substance using days and number of substances used at follow-up (βs = 0.04–0.06). In each case, associations were mediated by tendency to use substances to cope with the pandemic (β_indirect range: 0.028–0.061). To mitigate disproportionate escalation of substance use in young adults with a history of certain types of emotional disturbance, interventions promoting healthy coping strategies to deal with the pandemic’s social conditions warrant consideration.

摘要

COVID-19大流行病具有独特的压力源（例如，社会隔离），这可能会增加有情感障碍史的年轻人的物质使用风险。这项研究检查了青春期的情绪障碍症状和转诊易感性是否预测了在COVID-19期间使用年轻成人药物，以及是否使用药物来应对大流行的社会状况介导了这些关联。青少年（N = 2,120）完成了基线调查，评估了经诊断的情感脆弱性（快感缺乏症，窘迫不耐症，焦虑敏感性，紧急程度）和症状（严重抑郁[MD]，广泛性焦虑[GAD]，恐慌症[PD]，社交恐惧症[SP] ]，强迫症[OCD]），青春期（2016年9月至12月； M [ SD]年龄= 17.45 [0.38]）。在随访中（2020年5月至2020年8月； M [ SD ]年龄= 21.16 [0.39]），据报告，过去30天使用了毒品，并在大流行期间使用了毒品来应对社会隔离。调整后的模型显示，基线痛苦不耐症，焦虑敏感性，急迫性和MD症状均显着预测了过去一个月的单物质使用天数和随访时使用的物质数量较高（βs = 0.04-0.06）。在每种情况下，协会都是通过使用物质来应对大流行的趋势（β_间接范围：0.028–0.061）。为了减轻具有某些类型的情绪障碍史的年轻成年人中药物滥用的不成比例的上升，应考虑采取促进健康应对策略以应对大流行病社会状况的干预措施。