Despite substantial advances in the diagnosis and management, pulmonary embolism (PE) continues to be a significant cause of mortality. In this article, we provide a concise overview of the evolution of worldwide mortality trends related to PE. Despite the data being derived mainly from observational studies, there is a clear trend toward decreasing mortality over time from PE. Whether this truly represents a treatment effect or is more related to increased diagnosis of small PEs is not fully clear. Modern approaches to PE management such as the PE response teams have the potential to further reduce the mortality from PE.

中文翻译：

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急性肺栓塞的死亡率趋势

尽管在诊断和管理方面取得了重大进展，但肺栓塞 (PE) 仍然是导致死亡的重要原因。在本文中，我们简要概述了与 PE 相关的全球死亡率趋势的演变。尽管数据主要来自观察性研究，但随着时间的推移，PE 的死亡率明显呈下降趋势。这是否真正代表了一种治疗效果，还是与小 PE 的诊断增加有关，尚不完全清楚。PE 管理的现代方法，例如 PE 反应小组，有可能进一步降低 PE 的死亡率。