Cellular senescence has a critical role in many physiopathological contexts. Recent studies highlight the beneficial and adverse effects that eliminating senescent endothelial cells can have on health span, questioning the current development of drugs that induce the death of senescent cells, named senolytics, as a therapeutic strategy.

中文翻译：

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消除衰老内皮细胞：好还是坏主意？

细胞衰老在许多病理生理环境中具有关键作用。最近的研究强调了消除衰老内皮细胞可能对健康产生的有益和不利影响，质疑当前开发的诱导衰老细胞死亡的药物（称为 senolytics）作为一种治疗策略。