Biophysics Pub Date : 2021-03-11 , DOI: 10.1134/s0006350920060093 S. V. Kozin , A. A. Kravtsov , E. I. Zlischeva , L. V. Shurygina , V. V. Malyshko , A. V. Moiseev , A. A. Elkina , M. G. Baryshev
The effects of prolonged (42 day) consumption of deuterium-depleted water by rats on the functional state of their central nervous system under normal conditions and under conditions of normobaric hypercapnic hypoxia have been studied. The consumption of deuterium-depleted water both under normal conditions and after exposure to oxidative stress contributed to a significant reduction in emotional anxiety in animals. Prolonged consumption of deuterium-depleted water before experimental hypoxia (amnesic factor) helped animals to maintain their ability to learn and memory at the control level, i.e., it exerted a pronounced protective antiamnesic effect. Under normal conditions, deuterium-depleted water does not affect the learning ability of animals.
中文翻译:
贫氘饮食对缺氧动物中枢神经系统功能状态的影响
研究了正常条件下和常压高碳酸血症低氧条件下大鼠长时间(42天)消耗氘水对中枢神经系统功能状态的影响。在正常条件下以及暴露于氧化应激后消耗的氘水消耗量都极大地降低了动物的情绪焦虑。在实验性缺氧(记忆消除因子)之前长期消耗贫氘水有助于动物在控制水平上维持其学习和记忆的能力,即,发挥了显着的保护性记忆消除作用。在正常条件下,贫氘水不会影响动物的学习能力。