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Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
Royal Society Open Science ( IF 2.9 ) Pub Date : 2021-03-10 , DOI: 10.1098/rsos.200779
Huiquan Wang 1 , Meng Hu 2 , Fang Xia 1 , Meng Guo 1 , Shengzhao Zhang 3 , Zhe Zhao 2 , Guang Han 1 , Jinhai Wang 1
Affiliation  

In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality.



中文翻译:

基于快速数字锁定算法的荧光内窥镜图像信噪比增强

本文采用快速数字锁定算法增强了两个图像通道的信噪比(SNR)。为了同时提高荧光内窥镜获得的白色和荧光图像的质量,并提高信噪比以获得更好的图像处理效果,调制了荧光内窥镜的白光和近红外两种光源,然后采集图像被解调为白色和荧光图像。设置了荧光内窥镜实验平台,以获取由吲哚菁绿染色的目标的内窥镜图像。实验结果表明,没有锁定算法的白色和荧光图像的SNR分别为36.56 dB和33.47 dB。但是,使用锁定算法,白色和荧光图像的SNR分别为39.54 dB和35.70 dB,分别。通过应用数字锁定算法,白色和荧光图像的SNR分别提高了8.2%和6.7%。因此,这种基于快速数字锁定算法的新型荧光内窥镜可以快速,同时获得白光和荧光的两通道图像,有效提高白光和荧光图像的信噪比,提高成像质量。

更新日期:2021-03-10
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