Abstract

Objective

The objective of this study is to examine time perception impairment in multiple sclerosis (MS) patients.

Method

The study was performed with 60 MS patients and 60 age-matched healthy people. Estimation and Production Tests were carried out with a standard personal laptop computer and participants were aware to count the seconds by the ‘start’ command and to stop by the ‘stop’ command. The outcome measure was the ratio between the estimated duration and the target (7 s, 32 s, or 58 s) one for the Estimation Test and the Produced duration and the target (7 s, 32 s, or 58 s) one for the Production Test; and each time duration was repeated three times both for Production and Estimation Tests.

Results

We found a significant difference in the Estimation Test (7 s, 32 s, 58 s), and the Production Test (7 s, 32 s, 58 s) between the MS group and healthy control group (p < .05). It was observed that patients with MS had a higher deviation from the target time compared to the control group. It was found that this difference was statistically significant (p < .05). There was a high and negative correlation between the Estimation and Production Tests in MS patients.

Conclusion

In conclusion, our data suggests that time estimation and production are disturbed in MS patients, and cognitive rehabilitation is required for most of them.

中文翻译：

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多发性硬化患者的时间感知存在障碍

摘要

客观的

本研究的目的是检查多发性硬化症 (MS) 患者的时间感知障碍。

方法

该研究对 60 名 MS 患者和 60 名年龄匹配的健康人进行。估计和生产测试是用一台标准的个人膝上型计算机进行的，参与者知道通过“开始”命令计算秒数，并通过“停止”命令停止。结果测量是估计持续时间与目标（7 秒、32 秒或 58 秒）之间的比率，其中一项用于估计测试和生产持续时间，以及目标（7 秒、32 秒或 58 秒）之间的比率生产测试；对于生产和估计测试，每个持续时间重复 3 次。

结果

我们发现 MS 组和健康对照组之间的估计测试（7 秒、32 秒、58 秒）和生产测试（7 秒、32 秒、58 秒）存在显着差异（p  < .05）。据观察，与对照组相比，MS 患者与目标时间的偏差更大。发现这种差异具有统计学意义（p  < .05）。MS 患者的估计和生产测试之间存在高度的负相关。

结论

总之，我们的数据表明 MS 患者的时间估计和生产受到干扰，并且大多数患者需要认知康复。