Early life exposure to endocrine-disrupting chemicals (EDCs) is considered a potential risk factor for aberrant brain development and the emergence of behavioral deficits. The purpose of this review is to summarize the toxic effects of bisphenol-A (BPA) and phthalate exposure during pre-, -post- or perinatal life on different types of behaviour in male and female rodents. Despite results not being always consistent, most probably due to methodological issues, it is highly probable that early life exposure to BPA or/and phthalates, affects various aspects of behaviour in the offspring. Adverse effects include: Increased levels of anxiety, altered exploratory behaviour, reduced social interaction or increased aggression and deficits in spatial or recognition learning and memory. These effects have been observed with a wide range of doses, in some cases even below the currently employed Tolerable Daily Intake dose for either BPA or phthalates.

早年接触内分泌干扰化学物质 (EDC) 被认为是大脑发育异常和出现行为缺陷的潜在风险因素。本综述的目的是总结双酚 A (BPA) 和邻苯二甲酸酯暴露对雄性和雌性啮齿动物在产前、产后或围产期的不同类型行为的毒性影响。尽管结果并不总是一致，很可能是由于方法问题，但很可能早期接触 BPA 或/和邻苯二甲酸盐会影响后代行为的各个方面。不利影响包括： 焦虑水平增加、探索行为改变、社交互动减少或攻击性增加以及空间或识别学习和记忆能力不足。已在广泛的剂量范围内观察到这些影响，