Abstract

Using the templates preliminarily made by 3D design and prototyping methods, defects in the lateral area of the lower jaw of sheep were created using the piezosurgical technique. The defects were replaced by plastic implants obtained by the method of layer-by-layer fusion of the FDM printing–fusing deposition modeling and fixation with titanium screws to the jaw body. In the time interval, plastic implants are replaced by titanium implants obtained by selective laser sintering (SLS) using a 3D printer. To study the processes of reparative osteogenesis, microsamples of tissues of the preimplantation zone were analyzed. As a result, signs of osteo- and fibro-osseointegration were identified. The obtained data are regarded as a prerequisite for further clinical trials of the developed protocols for the sequential replacement of jaw defects using 3D printing.

中文翻译：

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使用初步的数字设计，顺序使用塑料和钛植入物对动物下颌骨缺损进行实验性置换的有效性

摘要

使用通过3D设计和原型制作方法预先制作的模板，使用压电外科技术在绵羊下颌的外侧区域产生缺陷。通过FDM打印的逐层融合方法（融合沉积模型并用钛螺钉将其固定在颚体上）获得的塑料植入物替代了缺损。在该时间间隔内，塑料植入物被钛植入物取代，而钛植入物是通过使用3D打印机进行选择性激光烧结（SLS）获得的。为了研究修复性成骨的过程，分析了植入前区域组织的微量样品。结果，鉴定出骨-和骨-骨整合的迹象。