Lung granulomas are uncommon in Thailand. The disease typically develops from an occupational environment and is mostly caused by infection. Herein is a case report of a female patient, aged 48, working as a nurse in an Accident and Emergency Department at a hospital. Eighteen years prior to admission the patient was diagnosed with myasthenia gravis and pulmonary tuberculosis. The chest X-ray and CT scans showed a solitary pulmonary nodule in the lower left lung. The patient received an open thoracotomy with a left lobectomy. Granulomatous and nonseptate hyphae were found in the pathology diagnosis. The patient was thus diagnosed as having a lung granuloma. The galactomannan antigen test was positive. The solitary pulmonary nodule—found from the use of a Polymerase Chain Reaction (PCR) test—was an Aspergillus spp. The fungus culture was collected from air samples. The air samples were collected by the impaction technique using a microbial air sampler. Three types of Aspergillus spp. were found as well as Penicillium spp. and Monilia sitophila. The Aspergillus spp. was a match for the patient's disease. The patient was diagnosed as having a lung granuloma possibly Aspergillus nodule which was caused by airborne Aspergillus spp. from the occupational environment.

肺肉芽肿在泰国并不常见。该疾病通常由职业环境发展而来，并且主要由感染引起。以下是一名 48 岁女性患者的病例报告，她在医院急症室担任护士。入院前 18 年，患者被诊断出患有重症肌无力和肺结核。胸部 X 线和 CT 扫描显示左下肺有一个孤立的肺结节。患者接受了左肺叶切除术的开胸手术。病理诊断中发现肉芽肿和无隔菌丝。因此，该患者被诊断为患有肺肉芽肿。半乳甘露聚糖抗原试验呈阳性。通过聚合酶链反应 (PCR) 测试发现的孤立性肺结节是一种曲霉菌属 从空气样品中收集真菌培养物。使用微生物空气采样器通过撞击技术收集空气样品。曲霉属的三种类型。被发现以及青霉菌属。和栉水母。该曲霉菌属。与患者的疾病相匹配。该患者被诊断为肺肉芽肿，可能是由空气中的曲霉属引起的曲霉结节。从职业环境来看。