Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2021-05-01 , DOI: 10.2174/1389557520666201009162804 Madhwi Ojha 1 , Divya Yadav 1 , Avinash Kumar 2 , Suman Dasgupta 3 , Rakesh Yadav 1
1, 8- Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic compounds which has garnered the interest of researchers due to its versatile biological activities. It is known to be used as an antimicrobial, anti-psychotic, anti-depressant, anti-convulsant, anti- Alzheimer’s, anti-cancer, analgesic, anti-inflammatory, antioxidant, anti-viral, anti-hypertensive, antimalarial, pesticides, anti-platelets, and CB2 receptor agonist, etc. The present review highlights the framework of biological properties of synthesized 1, 8-naphthyridine derivatives developed by various research groups across the globe.
中文翻译:
1,8-萘啶衍生物:多功能生物活动的特权支架。
1,8-萘啶核属于重要的含氮杂环化合物,由于其广泛的生物活性而引起了研究人员的兴趣。已知它被用作抗菌剂,抗精神病药,抗抑郁药,抗惊厥药,抗阿尔茨海默氏病,抗癌药,镇痛药,抗炎药,抗氧化剂,抗病毒药,抗高血压药,抗疟疾药,农药,本综述着重介绍了全球各个研究小组开发的合成的1,8,萘啶衍生物的生物学特性框架。