Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) first reached the United States in January 2020. Located in New York City (NYC), MSK Kids, at Memorial Sloan Kettering Cancer Center services, is one of the largest pediatric cancer centers in the U.S., caring for children, teenagers, and young adults with cancer, immune deficiencies, and blood disorders. Methods: Implementation for infection mitigation and ongoing care of patients included: (1) the creation of a strategic planning team of physicians, advanced practice providers, nurses, and administrators to develop guidance and workflows, (2) continuous reassessment of patients’ needs for hospital services and visit frequency, (3) the use of telemedicine to replace in-person visits, (4) the use of satellite regional centers to manage patients living outside NYC, (5) pre-screening of patients prior to visits for risks and symptoms of coronavirus disease 2019 (COVID-19) infection, (6) day-of-service screening for risks or symptoms of COVID-19 infection, (7) surveillance testing of children and their caregivers, and (8) creation of cohort plans for the management of COVID-19 positive and uninfected patients within the same institution, in both the outpatient and inpatient settings. Results: We describe the timeline for planning mitigation during the first weeks of the pandemic, and detail in a stepwise fashion the rationale and implementation of COVID-19 containment efforts in the context of a large pediatric oncology program. Discussion: Our experience offers a model on which to base strategic planning efforts at other pediatric oncology centers, for continued preparedness to combat the threat posed by SARS-CoV-2 worldwide.

背景：严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 于 2020 年 1 月首次到达美国。MSK Kids 位于纽约市 (NYC)，在斯隆凯特琳纪念癌症中心服务，是最大的癌症中心之一美国的儿科癌症中心，照顾患有癌症、免疫缺陷和血液疾病的儿童、青少年和年轻人。方法：减轻感染和持续护理患者的实施包括：(1) 创建由医生、高级实践提供者、护士和管理人员组成的战略规划团队，以制定指导和工作流程，(2) 持续重新评估患者对医院服务的需求和就诊频率，(3) 使用远程医疗代替亲自就诊，(4) 使用卫星区域中心管理居住在纽约市以外的患者，(5) 在就诊前对患者进行风险和症状预筛查2019 年冠状病毒病 (COVID-19) 感染，(6) 服务日筛查 COVID-19 感染的风险或症状，(7) 对儿童及其照料者进行监测测试，以及 (8) 制定队列计划在同一机构内管理 COVID-19 阳性和未感染患者，在门诊和住院环境中。结果：我们描述了在大流行的最初几周规划缓解的时间表，并在大型儿科肿瘤学项目的背景下逐步详细说明 COVID-19 遏制工作的原理和实施。讨论：我们的经验为其他儿科肿瘤中心的战略规划工作提供了一个模型，以继续准备应对全球 SARS-CoV-2 构成的威胁。