Purpose: Children with Down syndrome (DS) have multiple difficulties in gait pattern. So, the effect of the activity level and speed on the gait coordination and variability was investigated.

Methods: In this case-control observational study, 24 participants in three groups of active and non-active children with DS, and the control group without intellectual disability were asked to walk on a treadmill with two speeds of 0.8 and 1.2 m/s. Continuous Relative Phase (CRP) and variability of CRP in thigh-leg and leg-foot coupling were assessed.

Results: CRP and variability of CRP in the leg-foot coupling in the control group were significantly higher than active and non-active groups with DS. Speed led to increase the CRP of leg-foot in the active group with DS and increase the variability of this coupling in non-active group with DS.

Conclusion: In this study, the activity level provided the compatibility with speed changes of walking in CRP of leg-foot in children with DS.

目的：患有唐氏综合症 (DS) 的儿童在步态模式上有多种困难。因此，研究了活动水平和速度对步态协调性和变异性的影响。

方法：在这项病例对照观察性研究中，要求三组活跃和非活跃的 DS 儿童以及无智力障碍的对照组的 24 名参与者在跑步机上以 0.8 和 1.2 m/s 两种速度行走。评估了大腿-腿和腿-足耦合中 CRP 的连续相对相位 (CRP) 和变异性。

结果：对照组的CRP和CRP变异性在腿-足耦合中显着高于DS的活动组和非活动组。速度导致 DS 的活动组中腿脚的 CRP 增加，并增加了 DS 的非活动组中这种耦合的可变性。

结论：本研究中，活动水平与DS患儿腿足CRP的步行速度变化具有相容性。