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Advancement in our understanding of immune response against Encephalitozoon infection
Parasite Immunology ( IF 1.4 ) Pub Date : 2021-03-07 , DOI: 10.1111/pim.12828
Praisy Aseeja 1 , Yasmin Shaikh 1 , Anamika Bajpai 2 , Prachitee Sirsikar 1 , Sonali K Kalra 1
Affiliation  

Microsporidia are a group of obligate, intracellular, spore‐forming eukaryotic pathogens, which predominantly infects immunocompromised individuals worldwide. Encephalitozoon spp. is one of the most prevalent microsporidia known to infect humans. Host immune system plays a major role in combating pathogens including Encephalitozoon spp. infecting humans. Both innate and adaptive arms of host immune system work together in combating Encephalitozoon infection. Researchers are conducting studies to elucidate the role of both arms of immune system against Encephalitozoon infection. In addition to cell‐mediated adaptive immunity, role of innate immunity is also being highlighted in clearance of Encephalitozoon spp. from host body. Therefore, the current review will give a clear and consolidated update on the role of innate as well as adaptive immunity in protection against Encephalitozoon spp.

中文翻译:

我们对脑炎病毒感染免疫反应理解的进展

微孢子虫是一组专性的、细胞内的、形成孢子的真核病原体,主要感染全世界免疫功能低下的个体。脑炎虫属 是已知感染人类的​​最普遍的微孢子虫之一。宿主免疫系统在对抗包括脑炎病毒在内的病原体方面发挥着重要作用。感染人类。宿主免疫系统的先天性和适应性武器共同对抗脑炎病毒感染。研究人员正在进行研究,以阐明免疫系统的两个臂对脑炎病毒感染的作用。除了细胞介导的适应性免疫外,先天免疫在清除脑炎中的作用也受到重视属 从宿主身上。因此,当前的审查将对先天免疫和适应性免疫在预防脑炎病毒中的作用提供清晰和综合的更新。
更新日期:2021-05-11
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