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VS38 staining contributes to a novel gating strategy in flow cytometry for small B cell lymphoma, especially in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia
Cytometry Part B: Clinical Cytometry ( IF 2.3 ) Pub Date : 2021-03-07 , DOI: 10.1002/cyto.b.22000
Shumpei Mizuta 1, 2 , Noriko Yamane 1 , Saya Mononobe 1 , Asami Watanabe 1 , Shinichiro Matsuki 1 , Takao Komai 1 , Yusuke Koba 3 , Sachiko Mitani 3 , Takahito Kawata 3, 4 , Akira Tamekane 3 , Mitsumasa Watanabe 3
Affiliation  

Multi-parametric flow cytometry (MFC) is a helpful tool for detecting neoplastic cells in malignant lymphoma; however, lymphoma cells can be difficult to detect when characteristic immunophenotypic abnormalities are not evident. We evaluated the stainability of VS38, which is used for multiple myeloma, in normal and abnormal B cells using MFC to develop a new strategy for detecting lymphoma cells.

中文翻译:

VS38 染色有助于流式细胞术中小 B 细胞淋巴瘤的新门控策略,尤其是在淋巴浆细胞性淋巴瘤/Waldenström 巨球蛋白血症中

多参数流式细胞术 (MFC) 是检测恶性淋巴瘤中肿瘤细胞的有用工具;然而,当特征性免疫表型异常不明显时,淋巴瘤细胞可能难以检测。我们使用 MFC 评估了用于多发性骨髓瘤的 VS38 在正常和异常 B 细胞中的染色性,以开发一种检测淋巴瘤细胞的新策略。
更新日期:2021-03-07
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