The review considers general methods for the preparation of 3-amino-3-deoxy- and 4-amino-4-deoxyhexoses and their derivatives, including nitromethane condensation, reduction of 3- and 4-hexosulose oximes, epoxide opening with an azide ion, and nucleophilic substitution of sulfonates. The use of amino sugars of this type in the synthesis of natural carbohydrate-containing compounds and their analogues, including aminoglycoside antibiotics, glycosidase inhibitors, substrate analogues and inhibitors of glycan biosynthesis, galectin inhibitors, etc. is described.

The bibliography includes 89 references.

中文翻译：

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3-氨基-3-脱氧和 4-氨基-4-脱氧己糖在天然碳水化合物化合物及其类似物合成中的作用

该综述考虑了制备 3-氨基-3-脱氧和 4-氨基-4-脱氧己糖及其衍生物的一般方法，包括硝基甲烷缩合、3-和 4-己酮糖肟的还原、用叠氮离子打开环氧化物、和磺酸盐的亲核取代。此类氨基糖在合成含天然碳水化合物的化合物及其类似物中的用途，包括氨基糖苷类抗生素、糖苷酶抑制剂、底物类似物和聚糖生物合成抑制剂、半乳糖凝集素抑制剂等。被描述。

参考书目包括 89 篇参考文献。