Anxiety sensitivity (fear of potential negative consequences of anxiety-related symptoms/sensations) has been identified as a transdiagnostic factor in comorbid pain and nicotine dependence and evidence suggests that anxiety sensitivity may be indirectly associated with nicotine use via greater pain severity. Therefore, this study tested the hypothesis that anxiety sensitivity is associated with cigarette and e-cigarette use/co-use directly and indirectly via greater pain severity. Participants included 273 online survey respondents with chronic musculoskeletal pain (34% female; M_age = 32.9). Anxiety sensitivity was positively associated with cigarette smoking, e-cigarette use and cigarette/e-cigarette co-use (ps < .05). Furthermore, anxiety sensitivity was indirectly and positively associated with cigarette smoking, e-cigarette use and co-use via greater chronic pain severity. Pain severity may play an important role in associations between anxiety sensitivity and nicotine dependence and prospective research should examine temporal/causal effects of anxiety sensitivity in relation to pain severity and nicotine/tobacco use.

焦虑敏感性（对焦虑相关症状/感觉的潜在负面后果的恐惧）已被确定为共病疼痛和尼古丁依赖的跨诊断因素，并且证据表明焦虑敏感性可能通过更大的疼痛严重程度与尼古丁的使用间接相关。因此，这项研究测试了这样的假设：焦虑敏感性与香烟和电子烟的使用/共同使用直接或间接地通过更大的疼痛严重程度相关。参与者包括 273 名患有慢性肌肉骨骼疼痛的在线调查受访者（34% 为女性； M_年龄= 32.9）。焦虑敏感性与吸烟、使用电子烟和同时使用香烟/电子烟呈正相关 ( p s < .05)。此外，焦虑敏感性通过更严重的慢性疼痛与吸烟、电子烟的使用和共同使用呈间接正相关。疼痛严重程度可能在焦虑敏感性和尼古丁依赖之间的关联中发挥重要作用，前瞻性研究应检查焦虑敏感性与疼痛严重程度和尼古丁/烟草使用之间的时间/因果影响。