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The relationship between ambivalence, alexithymia, and salience network dysfunction in schizophrenia
Psychiatry Research: Neuroimaging ( IF 2.1 ) Pub Date : 2021-03-05 , DOI: 10.1016/j.pscychresns.2021.111271
Seon-Koo Lee , Jung Suk Lee , Yu-Bin Shin , Hesun Erin Kim , Byung-Hoon Kim , Jae-Jin Kim

Ambivalence in schizophrenia is worth investigating its association with salience processing and alexithymia using functional MRI. Twenty-two patients with schizophrenia and 22 healthy controls were scanned during the ambivalence task of matching picture (ambivalent, positive and negative) and word (positive and negative) stimuli, and the Toronto Alexithymia Scale (TAS) was rated. Patients exhibited decreased activity in the anterior cingulate cortex (ACC) and insula compared to controls, and ACC activity in the ambivalent condition was negatively correlated with the TAS score in patients. Ambivalence in schizophrenia may be based on salience network dysfunction, and this disturbance may be related to alexithymia.



中文翻译:

精神分裂症的矛盾心理,运动障碍和显着网络功能障碍之间的关系

精神分裂症的矛盾性值得使用功能性MRI研究其与突显加工和吞咽障碍的关系。在匹配图片(矛盾,正面和负面)和单词(正面和负面)刺激的矛盾任务期间,对22名精神分裂症患者和22名健康对照进行了扫描,并对多伦多Alexithymia量表(TAS)进行了评级。与对照组相比,患者在前扣带回皮质(ACC)和岛中显示出降低的活动,并且在矛盾状态下,ACC的活动与患者的TAS评分呈负相关。精神分裂症的环境不佳可能是基于显着网络功能障碍,这种紊乱可能与运动障碍有关。

更新日期:2021-03-09
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