Humoral immunity is critical for limiting Plasmodium parasite infections and the severity of malaria. Naturally acquired immunity against malaria occurs inefficiently and protection is relatively short-lived. Here we review recent advances and explore emerging hypotheses regarding the molecular and cellular pathways that regulate Plasmodium parasite-specific B cell responses and durable anti-malarial humoral immunity.

中文翻译：

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抗疟疾体液免疫：长与短

体液免疫对于限制疟原虫感染和疟疾的严重程度至关重要。对疟疾的自然获得性免疫力低下，保护时间相对较短。在这里，我们回顾了最近的进展，并探讨了关于调节疟原虫特异性 B 细胞反应和持久抗疟疾体液免疫的分子和细胞途径的新假设。