Recently, during the pandemic infection of the novel SARS-CoV-2, some cases of Miller Fisher syndrome (MFS) have been reported. We want to summarize the main features of patients with MFS and COVID-19. A PubMed search was performed on 8 October to identify references reporting cases with MFS associated with COVID-19 from the first report of COVID-19 to 8 October 2020 using the following keywords: “Miller Fisher syndrome” AND “COVID-19” OR “SARS-CoV-2”. A systematic review from the first report of coronavirus disease 2019 (COVID-19) to 8 October 2020 revealed 7 cases with Miller Fisher syndrome (MFS) associated with COVID-19. The 7 cases came from 5 countries but most of these patients were from Europe (85.7%), especially Spain. There are 5 cases of MFS diagnosed after the laboratory confirmation of SARS-CoV-2 infection. The mean onset time of MFS-associated neurological symptoms was 14.75 days after the diagnosis of COVID-19. However, the two remaining cases presented initially with MFS-associated neurological symptoms followed by the diagnosis of COVID-19. The most common symptoms of COVID-19-associated MFS were perioral paresthesias (57.1%), ataxia (57.1%), blurred vision (42.9), ophthalmoplegia (42.9), and generalized areflexia (42.9). However, more cohort and case-control studies are required to establish the epidemiological linkage.

最近，在新型SARS-CoV-2大流行感染期间，报告了一些米勒·费希尔综合征（MFS）病例。我们想要总结 MFS 和 COVID-19 患者的主要特征。 10 月 8 日进行了 PubMed 检索，以使用以下关键词识别报告与 COVID-19 相关的 MFS 病例的参考文献，从第一份 COVID-19 报告到 2020 年 10 月 8 日：“米勒·费希尔综合征”和“COVID-19”或“ SARS-CoV-2”。从第一份 2019 年冠状病毒病 (COVID-19) 报告到 2020 年 10 月 8 日的系统回顾显示，有 7 例与 COVID-19 相关的米勒·费希尔综合征 (MFS) 病例。这7例病例来自5个国家，但大多数患者来自欧洲（85.7%），尤其是西班牙。实验室确诊 SARS-CoV-2 感染后，诊断出 5 例 MFS。 MFS 相关神经系统症状的平均发作时间为诊断出 COVID-19 后的 14.75 天。然而，其余两例最初出现与 MFS 相关的神经系统症状，随后被诊断为 COVID-19。 COVID-19相关MFS最常见的症状是口周感觉异常（57.1%）、共济失调（57.1%）、视力模糊（42.9）、眼肌麻痹（42.9）和全身反射消失（42.9）。然而，需要更多的队列和病例对照研究来确定流行病学联系。