Cation-induced conformational and self-assembly transitions in designer peptides,Molecular Systems Design & Engineering

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Cation-induced conformational and self-assembly transitions in designer peptides
Molecular Systems Design & Engineering ( IF 3.2 ) Pub Date : 2021-2-15 , DOI: 10.1039/d0me00165a
Govind P. Maurya _{1,

2,

3,

4} , Jisha Babu _{1,

2,

3,

4} , V. Haridas _{1,

2,

3,

4}

Affiliation

Designer cystine-cored triazole-containing peptides self-assembled into spherical vesicles. These peptides resembling a Zn-finger ligand showed a conformational transition to a β-sheet secondary structure upon Cu²⁺ binding, resulting in the disruption of self-assembled vesicles.

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