Background: Brotizolam is a sedative-hypnotic thienotriazolodiazepine that is a benzodiazepine analog used for debilitating insomnia. Anxiety, depression, and sleep disorders occur in about 15% of pregnant and lactating women; however, no studies have examined brotizolam transfer across the placenta or its excretion into breast milk. In this case report, we assessed brotizolam concentrations in maternal and neonatal blood, cord blood, and breast milk.

中文翻译：

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怀孕和哺乳期间的溴替唑仑：母体血清、脐带血、母乳和新生儿血清中的溴替唑仑水平

背景：溴替唑仑是一种镇静催眠的噻吩并三唑并二氮杂卓，是一种苯二氮卓类似物，用于使失眠变得虚弱。大约 15% 的孕妇和哺乳期妇女会出现焦虑、抑郁和睡眠障碍；然而，没有研究检查溴替唑仑通过胎盘转移或排泄到母乳中。在本病例报告中，我们评估了母体和新生儿血液、脐带血和母乳中溴替唑仑的浓度。