Usual culture methods to identify pathogenic bacteria can be unsuccessful, particularly when working with fastidious organisms. We present a case of early periprosthetic knee joint infection with Ureaplasma parvum only identified using 16S ribosomal RNA PCR. This case represents the impact molecular methods of bacterial identification can have on clinical care allowing for more targeted antimicrobial therapy; something which is imperative in an era of increasing antimicrobial resistance.

中文翻译：

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16S rRNA PCR检测假体周围关节感染小脲原体

识别致病菌的常规培养方法可能不成功，尤其是在处理苛刻的生物体时。我们提出了一个早期假体膝关节感染的病例，仅使用 16S 核糖体 RNA PCR 鉴定了细小脲原体。这个案例代表了细菌鉴定的分子方法对临床护理的影响，允许更有针对性的抗菌治疗；在抗生素耐药性日益增加的时代，这是势在必行的事情。