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Efficacy of a Spatial Repellent for Control of Aedes-Borne Virus Transmission: A Cluster Randomized Trial in Iquitos, Peru
medRxiv - Public and Global Health Pub Date : 2021-08-03 , DOI: 10.1101/2021.03.03.21252148
Amy C. Morrison , Robert C. Reiner , William H. Elson , Helvio Astete , Carolina Guevara , Clara del Aguila , Isabel Bazan , Crystyan Siles , Patricia Barrera , Anna B. Kawiecki , Christopher M. Barker , Gissella M. Vasquez , Karin Escobedo-Vargas , Carmen Flores-Mendoza , Alfredo A. Huaman , Mariana Leguia , Maria E. Silva , Sarah A. Jenkins , Wesley R. Campbell , Eugenio J. Abente , Robert D. Hontz , Valerie A. Paz-Soldan , John P. Grieco , Neil F. Lobo , Thomas W. Scott , Nicole L. Achee

Background Over half the world’s population is at risk for viruses transmitted by Aedes mosquitoes, such as, dengue and Zika. The primary vector, Aedes aegypti, thrives in urban environments. Despite decades of effort, cases and the geographic range of Aedes-borne viruses (ABV) continue to expand. Rigorously proven vector control interventions that measure protective efficacy against ABV diseases is limited to Wolbachia in a single trial in Indonesia, and do not include any chemical intervention. Spatial repellents, a new option for efficient deployment, are designed to decrease human exposure to ABV by releasing active ingredients into the air that disrupt mosquito-human contact.

中文翻译:

空间驱虫剂控制伊蚊病毒传播的功效:秘鲁伊基托斯的一项集群随机试验

背景世界上一半以上的人口面临由伊蚊传播的病毒的风险,例如登革热和寨卡病毒。主要媒介埃及伊蚊在城市环境中茁壮成长。尽管经过了数十年的努力,伊蚊传播的病毒 (ABV) 的病例和地理范围仍在继续扩大。在印度尼西亚的一项试验中,经过严格证明的衡量对 ABV 疾病的保护功效的病媒控制干预措施仅限于沃尔巴克氏菌,并且不包括任何化学干预。空间驱虫剂是一种有效部署的新选择,旨在通过向空气中释放破坏蚊子与人类接触的活性成分来减少人类对 ABV 的暴露。
更新日期:2021-08-04
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