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Prolactin modifies the in vitro LPS-induced chemotactic capabilities in human fetal membranes at the term of gestation
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2021-03-04 , DOI: 10.1111/aji.13413 Estefanía Núñez-Sánchez 1 , María Del Pilar Flores-Espinosa 1 , Ismael Mancilla-Herrera 2 , Leticia González 1 , José Cisneros 3 , Andrea Olmos-Ortiz 1 , Braulio Quesada-Reyna 4 , Martha Granados-Cepeda 5 , Veronica Zaga-Clavellina 6
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2021-03-04 , DOI: 10.1111/aji.13413 Estefanía Núñez-Sánchez 1 , María Del Pilar Flores-Espinosa 1 , Ismael Mancilla-Herrera 2 , Leticia González 1 , José Cisneros 3 , Andrea Olmos-Ortiz 1 , Braulio Quesada-Reyna 4 , Martha Granados-Cepeda 5 , Veronica Zaga-Clavellina 6
Affiliation
Immune responses of fetal membranes involve the production of chemoattractant mediators causing infiltration of maternal and fetal leukocytes, intrauterine inflammation and potentially the disruption of maternal-fetal tolerance. Prolactin (PRL) has deep immunoregulatory effects in the fetal-maternal interface. We aimed to test the in vitro PRL effect upon chemotactic capacities of human fetal membranes.
中文翻译：
催乳素在妊娠期改变人胎膜中体外 LPS 诱导的趋化能力
胎膜的免疫反应涉及化学引诱介质的产生，导致母体和胎儿白细胞浸润、宫内炎症和可能破坏母胎耐受性。催乳素 (PRL) 在胎母界面具有深层免疫调节作用。我们旨在测试体外PRL 对人胎膜趋化能力的影响。
更新日期：2021-03-04
中文翻译：
催乳素在妊娠期改变人胎膜中体外 LPS 诱导的趋化能力
胎膜的免疫反应涉及化学引诱介质的产生，导致母体和胎儿白细胞浸润、宫内炎症和可能破坏母胎耐受性。催乳素 (PRL) 在胎母界面具有深层免疫调节作用。我们旨在测试体外PRL 对人胎膜趋化能力的影响。
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