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Recent advances in bioprinting technologies for engineering different cartilage-based tissues
Biomaterials Advances ( IF 5.5 ) Pub Date : 2021-03-04 , DOI: 10.1016/j.msec.2021.112005
Tarun Agarwal , Irene Chiesa , Dario Presutti , Vincent Irawan , Kiran Yellappa Vajanthri , Marco Costantini , Yasuhiro Nakagawa , Sheri-Ann Tan , Pooyan Makvandi , Ehsan Nazarzadeh Zare , Esmaeel Sharifi , Carmelo De Maria , Toshiyuki Ikoma , Tapas Kumar Maiti

Inadequate self-repair and regenerative efficiency of the cartilage tissues has motivated the researchers to devise advanced and effective strategies to resolve this issue. Introduction of bioprinting to tissue engineering has paved the way for fabricating complex biomimetic engineered constructs. In this context, the current review gears off with the discussion of standard and advanced 3D/4D printing technologies and their implications for the repair of different cartilage tissues, namely, articular, meniscal, nasoseptal, auricular, costal, and tracheal cartilage. The review is then directed towards highlighting the current stem cell opportunities. On a concluding note, associated critical issues and prospects for future developments, particularly in this sphere of personalized medicines have been discussed.



中文翻译:

用于不同软骨组织的生物打印技术的最新进展

软骨组织的自我修复和再生效率不足,促使研究人员设计出先进而有效的策略来解决这一问题。将生物印记引入组织工程学已经为制造复杂的仿生生物工程构建物铺平了道路。在这种情况下,当前的审查以对标准和高级3D / 4D打印技术的讨论及其对修复不同软骨组织(即关节,半月板,鼻中隔,耳廓,肋和气管软骨)的意义进行讨论。然后,本文将重点介绍当前的干细胞机会。最后,讨论了相关的关键问题和未来发展的前景,特别是在个性化药物领域。

更新日期:2021-03-11
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