Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells,Cell Proliferation

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Vitronectin‐activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells
Cell Proliferation ( IF 5.9 ) Pub Date : 2021-03-03 , DOI: 10.1111/cpr.13012
Jun Shen ₁ , Yaoyao Zhu ₁ , Shuo Zhang ₁ , Shuzhen Lyu ₁ , Cuicui Lyu ₂ , Zicen Feng ₃ , Dixie L. Hoyle ₄ , Zack Z. Wang ₄ , Tao Cheng _{1,

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Affiliation

Vitronectin (VTN) has been widely used for the maintenance and expansion of human pluripotent stem cells (hPSCs) as feeder‐free conditions. However, the effect of VTN on hPSC differentiation remains unclear. Here, we investigated the role of VTN in early haematopoietic development of hPSCs.

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