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Investigating new serological and tissue markers for the follow‐up of patients operated for alveolar echinococcosis
Parasite Immunology ( IF 1.4 ) Pub Date : 2021-03-02 , DOI: 10.1111/pim.12827
Anne-Pauline Bellanger 1, 2, 3 , Junhua Wang 4 , Houssein Gbaguidi-Haore 5 , Coralie Barrera 2, 3 , Solange Bresson-Hadni 1, 3 , Inti Zlobec 6 , Anja Lachenmayer 7 , Carine Richou 3, 8 , Celia Turco 9 , Bruno Gottstein 4 , Laurence Millon 1, 2, 3 , Guido Beldi 7
Affiliation  

Alveolar echinococcosis (AE) is characterized by a chronically progressing hepatic injury caused by Echinococcus multilocularis. Surgery presently remains the best curative option. Currently, biological predictive features derived from the resected specimens are not suitable to assess surgery efficacy. The present study was designed to investigate whether a selection of markers measured on the resected specimens exhibits predictive features related to parasite viability, or to a total elimination of the parasite, in addition to serological markers.

中文翻译:

研究新的血清学和组织标志物,用于肺泡包虫病手术患者的随访

肺泡棘球蚴病 (AE) 的特征是由多房棘球蚴引起的慢性进展性肝损伤。手术目前仍然是最好的治疗选择。目前,来自切除标本的生物学预测特征不适合评估手术疗效。本研究旨在调查在切除标本上测量的标记选择是否表现出与寄生虫生存能力相关的预测特征,或除了血清学标记外,是否与寄生虫的完全消除有关。
更新日期:2021-05-11
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