Microfluidic biochips or lab-on-a-chip systems are controlled by the actuation sequences designed for some specific bioprotocols. Different attacks specifically, hardware Trojans in diagnostic kits like microfluidic biochips can jeopardize the healthcare industries. As the actuation sequence is also a piece of information, which can be altered by hardware Trojans, man-in-the-middle attacks, etc., it is essential to design a security model with some proper encryption techniques in order to make biochip designs trustworthy. Thus, in this paper, we present a security model for avoiding intellectual property theft of actuation sequences for microfluidic biochips in each stage of the biochip design flow. Furthermore, we describe systematic algorithms to minimize the time requirements for achieving the desired goals so that the chance of an attack is reduced, and hence, to enhance the security concerns of microfluidic biochips. Simulation results demonstrate that the proposed security model leads to maintain the time-to-result while not exceeding the completion time of different bioprotocols. The proposed scheme, which used AES as an encryption algorithm with a 128-bit encryption key, has also shown a speedup of 8.5 (with 88% efficiency) faster than the prior efficient scheme.

微流体生物芯片或芯片实验室系统由为某些特定生物协议设计的启动序列控制。特别是不同的攻击，诸如微流控生物芯片之类的诊断工具包中的硬件木马会危害医疗保健行业。由于启动序列也是一条信息，可以通过硬件特洛伊木马，中间人攻击等进行更改，因此必须使用一些适当的加密技术来设计安全模型，以便进行生物芯片设计值得信赖。因此，在本文中，我们提出了一种安全模型，可避免在生物芯片设计流程的每个阶段中，微流控生物芯片的启动序列的知识产权被盗。此外，我们描述了系统的算法，以最小化实现所需目标的时间要求，从而减少了攻击的机会，从而增强了微流控生物芯片的安全性。仿真结果表明，所提出的安全模型可以在不超过不同生物协议的完成时间的情况下，保持结果的时间。提议的方案使用AES作为具有128位加密密钥的加密算法，与先前的高效方案相比，还显示出8.5的加速速度（效率为88％）。