Aflatoxin B₁ is the most toxic mycotoxin and has strong carcinogenicity. In this study, coumarin was employed as the sole carbon source to isolate the microorganisms that had AFB₁ detoxification activity. Among106 strains isolated from fermented foods, one potential strain was identified as Lactobacillus plantarum based on 16 S rDNA sequence. Removal ratio of AFB₁ was 89.5%, inhibitory ratio to A. flavus growth was 42.8% and inhibitory ratio to A. flavus spores growth was as high as 100%. Coumarin utilization indicated that the AFB₁ could be decomposed by the strain. The strong antifungal ability against A. flavus growth and spores growth revealed that AFB₁ secretion could be highly inhibited by the strain. In addition, High Performance Liquid Chromatography analysis indicated that fermentation supernatant of the strain could degrade AFB₁. Scanning Electron Microscopy and Transmission Electron Microscopy indicated that the strain had a strong resistance to AFB₁ and had ability to bind AFB₁ on the strain surface. Possible detoxification pathway to AFB₁ was proposed. Therefore, the strain with high antifungal, antimycotoxigenic abilities might have great potential and immense value in detoxifying AFB₁. The use of the strain might be a promising biocontrol strategy to detoxify AFB₁.

黄曲霉毒素B ₁是最具毒性的霉菌毒素，具有很强的致癌性。在这项研究中，香豆素被用作唯一的碳源来分离具有AFB ₁解毒活性的微生物。从发酵食品中分离的106个菌株中，根据16 S rDNA序列鉴定出一种潜在的菌株为植物乳杆菌 。AFB _1的去除率为89.5％，对黄曲霉生长的抑制率为42.8％，对黄曲霉孢子生长的抑制率高达100％。香豆素的利用表明AFB ₁可以被菌株分解。对黄曲霉有很强的抗真菌能力生长和孢子生长表明该菌株可高度抑制AFB _1的分泌。另外，高效液相色谱分析表明该菌株的发酵上清液可以降解AFB ₁。扫描电子显微镜和透射电子显微镜表明，该菌株对AFB ₁具有很强的抗性，并具有在菌株表面上结合AFB _1的能力。提出了可能的通往AFB _1的排毒途径。因此，具有高抗真菌，抗霉菌毒素能力的菌株在解毒AFB _1方面可能具有巨大的潜力和巨大的价值。使用该菌株可能是一种有前途的生物防治策略，可以使AFB ₁排毒。。