U.S. computing leaders, including the National Science Foundation, have partnered with universities, government agencies, and the private sector to accelerate research into responses to COVID-19—providing an unprecedented collection of resources that include some of the fastest computers in the world. This article expands on last month's Leadership Computing article by continuing to showcase the range of contributions that the national cyberinfrastructure is making global efforts to stop the pandemic. This article touches on research efforts to learn how SARS-CoV-2 spreads among different populations, the biology and structure of the virus, and its mechanisms of infection, and to develop effective vaccines for prevention and antiviral therapies for treatment. Even though we are still early in the process of developing an effective therapeutic response, the rapid mobilization of the national research cyberinfrastructure is a timely reminder of the strategic importance of robust, ongoing investments in large-scale scientific computing.

中文翻译：

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对抗COVID-19的大规模科学计算

包括美国国家科学基金会在内的美国计算机领导者已与大学，政府机构和私营部门合作，以加快对COVID-19响应的研究，从而提供了前所未有的资源收集，其中包括世界上最快的计算机。本文在上个月的《领导力计算》一文的基础上进行了扩展，继续展示了国家网络基础设施正在全球范围内努力制止该大流行的各种贡献。本文着眼于研究工作，以了解SARS-CoV-2如何在不同人群中传播，病毒的生物学和结构及其感染机理，并开发出用于预防和治疗的有效疫苗。