Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of the present study was, for the host factors associated with different FMDV infections in cattle during the acute phase, to compare these factors’ influence on the expression of the IL-10, TLR-2, TNF-α, CXCL10, CD48, NFATC4 and IFNG inflammatory and immune-related genes.

中文翻译：

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埃及急性口蹄疫病毒感染牛炎症及免疫相关基因的比较表达分析

口蹄疫是一种传染性很强的病毒性疾病，影响所有偶足家畜。三种口蹄疫病毒 (FMDV) 血清型 A、O 和 SAT2 目前是埃及易感动物面临的最大威胁。本研究的目的是针对与牛在急性期不同的口蹄疫感染相关的宿主因素，比较这些因素对IL-10、TLR-2、TNF-α、CXCL10、CD48表达的影响。 , NFATC4和IFNG炎症和免疫相关基因。