Treating recurrent depression is a challenge for clinical practitioners. We investigated which family environmental factors contribute to differences between recurrent and non-recurrent depression by the young adulthood of the former adolescent inpatients. The initial sample covered 237 adolescent psychiatric inpatients with depression, of which 35.4% had later diagnosed with recurrent depression. Recurrence in depression was associated to distant maternal relationships in both male (p = 0.022) and female patients (p = 0.042). In females, the likelihood for recurrent depression was also related to psychiatric problems of the father (p = 0.013) and siblings (OR = 3.7, p = 0.032), and having a grand multiparous mother (p = 0.005). Our results emphasise the need for effective family-centred approaches in treatment of adolescents with depression.

治疗复发性抑郁症对临床医生来说是一个挑战。我们调查了哪些家庭环境因素导致前青少年住院患者的青年期复发性和非复发性抑郁症之间的差异。最初的样本覆盖了 237 名患有抑郁症的青少年精神科住院患者，其中 35.4% 后来被诊断为复发性抑郁症。在男性（p = 0.022）和女性患者（p = 0.042）中，抑郁症的复发与远亲关系有关。在女性中，复发性抑郁症的可能性也与父亲 (p = 0.013) 和兄弟姐妹 (OR = 3.7, p = 0.032) 的精神问题以及有一个大经产母亲 (p = 0.005) 有关。我们的研究结果强调需要有效的以家庭为中心的方法来治疗青少年抑郁症。