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Epidemiology of CNS tumours

Lauren Ackroyd, Azzam Ismail

Leeds Teaching Hospitals, Leeds, United Kingdom

The aim of the study is to identify the epidemiology of CNS tumours within the West Yorkshire region in comparison to other regions. The study aims to identify if any links can be made between the type or site of CNS tumour and the initial clinical symptoms. It also aims to identify if there is any link between occupation and incidence of CNS tumour.

All CNS pathology reports created at Leeds Teaching Hospital between 01/01/2019 and 09/03/2020 were analysed. The histological diagnosis and biopsy site were recorded and the corresponding medical records were used to identify age, gender, occupation and presenting clinical symptoms. Duplicate biopsies and cases where the corresponding medical records could not be identified were excluded. A total of 448 reports were included in the study.

The results showed that 13.12% of the samples included in the study represent metastatic disease. The majority being a breast, lung or melanoma as a primary. The most prevalent histological subtypes were meningioma and glioblastoma. The most prevalent group of primary CNS tumours with a total of 26.79% of all the samples was the diffuse astrocytic and oligodendroglial tumours. In this group the top 3 occupations identified were in the healthcare sector, IT and administration, and the retail sector. The most prevalent symptoms in this group were headaches, dysarthria and weakness. Further comparisons and analysis have been drawn across all CNS tumours identified in the study.

中文翻译：

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海报文摘

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中枢神经系统肿瘤的流行病学

劳伦·阿克罗伊德（Lauren Ackroyd），阿扎姆·伊斯梅尔（Azzam Ismail）

利兹教学医院，利兹，英国

该研究的目的是确定西约克郡地区与其他地区相比中枢神经系统肿瘤的流行病学。该研究旨在确定CNS肿瘤的类型或部位与初始临床症状之间是否有任何联系。它还旨在确定中枢神经系统肿瘤的职业与发病率之间是否存在任何联系。

分析了利兹教学医院在01/01/2019至09/03/2020之间创建的所有CNS病理报告。记录组织学诊断和活检部位，并使用相应的医学记录来识别年龄，性别，职业并表现出临床症状。重复活检和无法识别相应病历的病例被排除在外。该研究总共包括448个报告。

结果表明，研究中包括的13.12％的样品代表转移性疾病。多数以乳腺，肺或黑色素瘤为主。最普遍的组织学亚型是脑膜瘤和胶质母细胞瘤。原发性中枢神经系统肿瘤中最普遍的一组，占所有样本的26.79％，是弥漫性星形胶质细胞瘤和少突胶质细胞瘤。在该组中，确定的前3个职业是医疗保健部门，IT和管理以及零售部门。该组中最常见的症状是头痛，构音障碍和虚弱。已对研究中发现的所有中枢神经系统肿瘤进行了进一步的比较和分析。