Periprosthetic joint infections (PJIs) and osteomyelitis are clinical challenges that are difficult to eradicate. Well-characterized large animal models necessary for testing and validating new treatment strategies for these conditions are lacking. The purpose of this study was to develop a rabbit model of chronic PJI in the distal femur.

中文翻译：

---

用于慢性假体周围关节感染的大型动物兔模型的开发。

假肢周围感染（PJI）和骨髓炎是难以消除的临床挑战。缺乏测试和验证针对这些疾病的新治疗策略所必需的，特征明确的大型动物模型。这项研究的目的是建立股骨远端慢性PJI的兔子模型。