Mg-based thin film metallic glasses (TFMGs) can viably decrease stress shielding caused by mismatch of the modulus of elasticity between the implant material and human bone. Here, Mg-based TFMGs were fabricated onto implantable substrates by ion assisted pulsed DC magnetron sputtering. The microstructure assessment and the impact of the principle constituents of the coatings were determined utilizing an x-ray diffractometer, a transmission electron microscope, and x-ray photoelectron spectroscopy. The hardness of these thin films was estimated to be 5.1 GPa. In vitro degradation tests including electrochemical studies and immersion tests in simulated body fluid revealed that the presence of zinc could raise the corrosion resistance of Mg-based TFMG. Indirect in vitro cytotoxicity using L929 fibroblast cells revealed that the TFMGs did not induce any toxicity in cells. Biomineralization experiments using Saos-2 cells promoted the formation of calcium phosphate on its surface.

中文翻译：

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用于生物植入物的磁控溅射镁基薄膜金属玻璃

镁基薄膜金属玻璃 (TFMG) 可以有效地减少由于植入材料和人体骨骼之间的弹性模量不匹配而引起的应力屏蔽。在这里，通过离子辅助脉冲直流磁控溅射将镁基 TFMG 制造到可植入衬底上。使用 x 射线衍射仪、透射电子显微镜和 x 射线光电子能谱确定涂层的微观结构评估和主要成分的影响。这些薄膜的硬度估计为 5.1 GPa。体外降解试验包括电化学研究和模拟体液浸泡试验表明，锌的存在可以提高镁基 TFMG 的耐腐蚀性。间接体外使用 L929 成纤维细胞的细胞毒性表明 TFMG 不会在细胞中诱导任何毒性。使用 Saos-2 细胞的生物矿化实验促进了其表面磷酸钙的形成。