Patients with left breast cancer who undergo radiotherapy have a non-negligible risk of developing radiation-induced cardiovascular disease (CVD). Cardioprotection can be achieved through better treatment planning protocols and through respiratory gating techniques, including deep inspiration breath hold (DIBH). Several dosimetric studies have shown that DIBH reduces the cardiac dose, but clinical data confirming this effect is limited. The aim of the study was to compare the mean heart dose (MHD) in patients with left breast cancer who underwent radiotherapy at our institution as we transitioned from non-gated free-breathing (FB) radiotherapy to gated radiotherapy (FB-GRT), and finally to DIBH.

中文翻译：

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深吸气屏气可降低左侧乳腺癌放疗的平均心脏剂量

接受放疗的左乳腺癌患者发生辐射诱发的心血管疾病 (CVD) 的风险不可忽视。通过更好的治疗计划方案和呼吸门控技术，包括深吸气屏气 (DIBH)，可以实现心脏保护。几项剂量学研究表明，DIBH 可降低心脏剂量，但证实这种作用的临床数据有限。该研究的目的是比较在我们机构接受放疗的左乳腺癌患者在我们从非门控自由呼吸 (FB) 放疗过渡到门控放疗 (FB-GRT) 时的平均心脏剂量 (MHD)，最后到DIBH。