Molecular and biological features of Culex quinquefasciatus homozygous larvae for two cqm1 alleles that confer resistance to Lysinibacillus sphaericus larvicides,Pest Management Science

当前位置： X-MOL 学术 › Pest Manag. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Molecular and biological features of Culex quinquefasciatus homozygous larvae for two cqm1 alleles that confer resistance to Lysinibacillus sphaericus larvicides
Pest Management Science ( IF 3.8 ) Pub Date : 2021-02-28 , DOI: 10.1002/ps.6349
Heverly Suzany G Menezes ₁ , Nathaly A Nascimento ₁ , Milena Paiva-Cavalcanti ₂ , Samara G da Costa-Latgé ₃ , Fernando A Genta ₃ , Cláudia Mf Oliveira ₁ , Tatiany P Romão ₁ , Maria Helena Nl Silva-Filha ₁

Affiliation

Culex quinquefasciatus resistance to the binary toxin from Lysinibacillus sphaericus larvicides can occur because of mutations in the cqm1 gene that prevents the expression of the toxin receptor, Cqm1 α-glucosidase. In a resistant laboratory-selected colony maintained for more than 250 generations, cqm1_REC and cqm1_REC-2 resistance alleles were identified. The major allele initially found, cqm1_REC, became minor and was replaced by cqm1_REC-2. This study aimed to investigate the features associated with homozygous larvae for each allele to understand the reasons for the allele replacement and to generate knowledge on resistance to microbial larvicides.

中文翻译：

两个 cqm1 等位基因的库蚊纯合子幼虫的分子和生物学特征，这些等位基因赋予对球形赖氨酸杆菌杀幼虫剂的抗性

由于cqm1基因的突变阻止毒素受体Cqm1 α-葡萄糖苷酶的表达，因此可能会出现库蚊对来自杀球形赖氨酸芽孢杆菌的二元毒素的抗性。在一个维持了 250 多代的抗性实验室选择的菌落中，鉴定了cqm1 _REC和cqm1 _REC-2抗性等位基因。最初发现的主要等位基因cqm1 _REC变小并被cqm1 _REC-2取代. 本研究旨在调查与每个等位基因纯合幼虫相关的特征，以了解等位基因替换的原因并产生对微生物杀幼虫剂抗性的知识。

更新日期：2021-02-28

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11