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Nanostructured Carbon Fiber Modified by Silver Nanoparticles for the Medical Application
Powder Metallurgy and Metal Ceramics ( IF 0.9 ) Pub Date : 2021-03-01 , DOI: 10.1007/s11106-021-00191-8
V.P. Sergeev , O.B. Loginova , L.D. Kisterska , N.V. Boshytska , V.D. Klipov

In this work, the feasibility of synthesizing new composite system for the medical application using an activated carbon fiber nanostructured materials with silver nanoparticles through immobilization by adsorption from solutions (ACFNM/AgNP) has been studied. The stability of the obtained composite system in physiological solutions as a modern sorption application form has been examined. Optimal modes of carbonized fabric activation are proposed for synthesis of nanostructured carbon fiber with high sorption capacity. The size distribution of silver nanoparticles after the ultrasonic treatment of the original silver solution in glycerol was proved to significantly decrease in the size of the agglomerates formed in the solution. It has been shown that after ultrasonic treatment, the silver nanoparticles were actively adsorbed by the porous structure of the carbon matrix. Treatment of carbon fiber with silver nanoparticles showed their uniform adsorption on the surface of the carbon matrix to form silver agglomerates with sizes of ~90–120 nm and 250– 300 nm. When studying the physicochemical stability of the obtained composite systems in biological solutions it was revealed that the intensity of silver release from the surface of the ACFNM/AgNP composite depends on the volumetric capacity of the carbon matrix, the initial concentration of silver in the solution, and the chemical composition of biological media. At that, the amount of silver in the water filtrate was established to be greater than in physiological solutions after the interaction. It was shown that the initial silver concentration of 25 mg/L in a suspension of glycerol is most optimal for creating of stable ACFNM/AgNP composite systems. Besides, the slower release of silver from the surface of carbon matrices into physiological solutions of different salt composition ensures a prolonged effect of silver in modern sorption application forms for medical purposes. The ACFNM/AgNP composite system with a capacity of carbon matrix of 1.0 cm3/g and an initial concentration of silver in a solution of 25 mg/L was recommended for the future development of modern application materials.



中文翻译:

银纳米粒子修饰的纳米结构碳纤维在医学上的应用

在这项工作中,研究了通过将活性炭纤维纳米结构材料与银纳米颗粒通过溶液吸附固定化(ACFNM / AgNP)合成新的医疗应用复合系统的可行性。作为现代吸附应用形式,已经检查了所得复合体系在生理溶液中的稳定性。提出了碳化织物活化的最佳方式,用于合成具有高吸附能力的纳米结构碳纤维。原始银溶液在甘油中的超声处理后,银纳米颗粒的尺寸分布被证明可以显着减小溶液中形成的附聚物的尺寸。已经证明,在超声处理之后,银纳米颗粒被碳基质的多孔结构主动吸附。用银纳米颗粒处理碳纤维显示出它们在碳基质表面上的均匀吸附,形成大小为〜90–120 nm和250–300 nm的银团块。在研究所得复合系统在生物溶液中的物理化学稳定性时,发现从ACFNM / AgNP复合物表面释放的银的强度取决于碳基质的体积容量,溶液中银的初始浓度,以及生物介质的化学成分。那时,在相互作用后,水滤液中的银含量被确定为大于生理溶液中的银含量。结果表明,甘油悬浮液中银的初始浓度为25 mg / L对于创建稳定的ACFNM / AgNP复合系统是最理想的。此外,银从碳基质表面缓慢释放到不同盐组成的生理溶液中,确保了在现代医学用途的吸附应用形式中,银的作用延长。ACFNM / AgNP复合系统,碳基质容量为1.0 cm3 / g,建议将银在溶液中的初始浓度为25 mg / L,以用于现代应用材料的未来开发。

更新日期:2021-03-01
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