Traditional Chinese medicine (TCM) prescription or rumen-protected GABA (RP-GABA) can effectively relieve the heat stress (HS) in cattle, but the joint effects of TCM and RP-GABA on HS in beef cattle are not fully clarified. To investigate the effects of TCM or/and RP-GABA on growth performance, antioxidant capacity, serum parameters and heat shock proteins (HSPs) expression in beef cattle under HS ambient. A total of 40 Jinjiang yellow cattle were randomly divided into four groups: (a) control group (basal diet, BD), (b) TCM group (BD+TCM), (c) GABA group (BD+RP-GABA) and (d) TCM+GABA group (BD+TCM plus RP-GABA). Results indicated that the average daily feed intake (ADFI) was significantly elevated in the TCM+GABA group (p < 0.05), whereas, average daily gain (ADG) was elevated (p < 0.05) in the group of TCM (38.5%), GABA (35.4%) and TCM+GABA (41.5%) compared with the control group. Meanwhile, TCM+GABA exhibited prominently more positive effects in terms of SOD, BUN, T-CHO, TG, HDL-C and HSP70 (p < 0.05 or p < 0.01) than the control and other treatment groups. Therefore, TCM or GABA can effectively moderate the HS response in beef cattle by ameliorating antioxidant capacity, serum parameters and HSPs expression, meanwhile, the combination of them exerts a synergistic effect on HS alleviation.

中文翻译：

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中药组方与瘤胃保护γ-氨基丁酸对热应激肉牛的协同作用

中药（TCM）处方或瘤胃保护GABA（RP-GABA）可有效缓解牛热应激（HS），但中药与RP-GABA对肉牛热应激的联合作用尚未完全阐明。研究中药或/和 RP-GABA 对 HS 环境下肉牛生长性能、抗氧化能力、血清参数和热休克蛋白 (HSPs) 表达的影响。将 40 头晋江黄牛随机分为 4 组：（a）对照组（基础日粮，BD），（b）中药组（BD+TCM），（c）GABA 组（BD+RP-GABA）和(d) TCM+GABA 组 (BD+TCM 加 RP-GABA)。结果表明，TCM+GABA组平均日采食量（ADFI）显着升高（p  < 0.05），而平均日增重（ADG）升高（p < 0.05)中药组(38.5%)、GABA(35.4%)和中药+GABA(41.5%)与对照组比较。同时，TCM+GABA对SOD、BUN、T-CHO、TG、HDL-C和HSP70的积极作用明显优于对照组和其他治疗组（p  < 0.05或p  < 0.01）。因此，中药或 GABA 可以通过改善抗氧化能力、血清参数和 HSPs 表达来有效调节肉牛的 HS 反应，同时它们的组合对 HS 缓解具有协同作用。