Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET-EN), in South African women,American Journal of Reproductive Immunology

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Genital and systemic immune effects of the injectable, contraceptive norethisterone enanthate (NET-EN), in South African women
American Journal of Reproductive Immunology ( IF 3.6 ) Pub Date : 2021-02-28 , DOI: 10.1111/aji.13411
Refilwe P Molatlhegi _{1,

2} , Samkelisiwe Ngcobo _{1,

2} , Lenine J P Liebenberg _{1,

2} , Sinaye Ngcapu _{1,

2} , Amanda Mabhula ₃ , Alasdair Leslie ₃ , Nobuhle Mchunu _{1,

4,

5} , Mthobisi M Zondi ₁ , John H Adamson ₃ , Katya Govender ₃ , Natasha Samsunder ₁ , Salim S Abdool Karim _{1,

6} , Quarraisha Abdool Karim _{1,

6} , Jo-Ann S Passmore _{1,

7} , Aida Sivro _{1,

2,

8} , Lyle R McKinnon _{1,

8,

9}

Affiliation

Injectable hormonal contraceptives (IHC) have been associated with altered mucosal and systemic milieu which might increase HIV risk, but most studies have focused on DMPA and not NET-EN, despite the growing popularity and lower HIV risk associated with the latter in observational studies.

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